There are many therapeutic benefits to intravenous nicotinamide adenine dinucleotide (BR+ NAD) therapy for anti-aging. BR+ NAD has been known to decline with age, therefore detrimentally affecting the natural repair system within the cell. One of the important benefits of adding BR+ NAD into cells is the activation of restorative enzymes involved with regulating inflammation.
BR+ NAD is a coenzyme of Vitamin B3 (niacin), which helps by binding to other protein molecules to activate an enzyme. Enzymes are responsible for thousands of different biochemical reactions throughout the body and BR+ NAD assists in more reactions than any other vitamin molecule.
How Do NAD+ Levels Decrease as One Gets Older?
NAD+ is one of the body’s most important molecules and slowly loses it with its age due to the inability of the cell to recycle and form new NAD+, which results in a variety of health issues. Two enzymes that degrade NAD+ are CD38 and PARP.
Reverse Age by Replenishing NAD+
A new scientific discovery, done by David Sinclair, Ph.D., Professor of Genetics at Harvard University, reveals a possible solution to aging. Scientists at Harvard Medical School discovered a way to reverse and restore DNA damage. In the latest issue of Science explains how NAD+ plays a vital role in protein interaction and repairs DNA.
“Our results unveil a key mechanism in cellular degeneration and aging, but beyond that, they point to a therapeutic avenue to halt and reverse age-related and radiation-induced DNA damage,” said senior author David Sinclair, Ph.D., Professor of Genetics at Harvard University.
Poly (ADP-ribose) polymerases (PARPs) are enzymes that participate in replication, recombination and repairing damaged DNA. Inflammation and oxidative stress are often the cause for DNA damage. Macronutriends cannot convert into cellullar energy in the form of adenosine triphosphate (ATP) without NAD+, which will trigger the death of the cell.
NAD+ Activates Sirtuin Enzymes
Sirtuins are a type of NAD+ dependent, where it is required to activate NAD+. There are seven functions of sirtuin enzymes that function to turn on and off gene expression. Many of these genes have been linked to regulating inflammation while also creating more energy. Sirtuins are known to counter the decline in health that accompanies aging and other inflammatory-related diseases.
NAD+ Has Been Known to Reduce Inflammation
Because CD38 enzyme is a major regulator of NAD+ it has been theorized that by depleting CD38, it reverses age-related NAD+ and improves several aging factors, muscle function, and energy level.
A study has shown a correlation that NAD+ levels increase by simply inhibiting the CD38 enzyme. In order to produce a second messenger cADPR which regulates calcium within the cell, CD38 needs to consume one hundred molecules of NAD, therefore creating a negative domino effect which then inhibits sirtuin 1.
What Conditions Can BR+ NAD Therapy Help With?
What Makes Us The Best Choice For BR+ NAD Treatment in New Jersey?
At New Jersey NADBR+, each and every patient has their own treatment plan based on their condition, so treatments can vary anywhere from 4 to 15 days. Clients receive IV therapy under the care and supervision of Dr. Johanan Rand, M.D. and his qualified staff.
The setting is a calm and quiet environment which allows for a peaceful environment while IV Therapy is administered.
BR+ NAD therapy anecdotally has a positive effect when combined with other advanced therapies offered at New Jersey NADBR+ treatment center.